Tretizen-20 contains the active ingredient isotretinoin. Isotretinoin is a retinoid also known as 13-cis-retinoic acid. Systemic retinoids containing isotretinoin have improved the quality of life for many people, including preventing scar formation. Isotretinoin therapy gives complete remission of the disease for almost all people with acne, and after the end of the therapy course remission can last up to several months or even years.
Isotretinoin has the ability to treat the following skin conditions:
Drugs with isotretinoin are also very effective for the treatment of gram-negative folliculitis and pyoderma of the face. Gram-negative folliculitis is a complication that very often develops in patients with acne after using local and systemic antibacterial drugs.
The mechanism of isotretinoin action is not well understood, but it is known that it strongly suppresses the activity of the sebaceous glands. It suppresses both the activity of sebocytes (these are cells in the composition of the sebaceous glands, which secrete fatty secretions), and their proliferation, i.e. reproduction. Accordingly, as a result of the use of isotretinoin, both the secretion of sebum (secretion of the sebaceous glands) decreases, and the sebaceous glands decrease in size.
In addition, isotretinoin contributes to an indirect decrease in the number of Cutibacterium acnes (P.acnes) bacteria, normalizes the processes of follicular keratinization, and also has anti-inflammatory action.
Tretizen-20 by Zenlabs is manufactured in the form of capsules that contain 20mg of isotretinoin. The recommended dosage is 1 tablet (20mg) per day.
Complete reduction of acne symptoms can be achieved within 15 to 20 weeks after taking isotretinoin. An improvement in the condition of your acne can even be observed within 1-2 months after discontinuation of the drug.
The severity of adverse reactions always depends on the daily dose of isotretinoin. Most of the side effects will be associated with the skin and mucous membranes. The most common side effects are:
With proper administration, side effects should be minimal. If you need any advice about Tretizen-20 or the use of this product, then please feel free to contact us and we can help you with this.